Analysis of risk factors associated with lymph node metastasis and prognosis of T1-2 colorectal cancer / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
; (12): 245-248, 2011.
Article
in Zh
| WPRIM
| ID: wpr-237137
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate factors associated with lymph node metastasis and prognosis in patients with T1-2 colorectal cancer.</p><p><b>METHODS</b>Patients with pT1-2 colorectal cancer between January 1999 to January 2005 were included. Chi-square test and multivariable logistic analysis were performed to evaluate risk factors associated with lymph node metastasis. Survival outcomes were analyzed using Kaplan-Meier and Cox regression model.</p><p><b>RESULTS</b>Tumor location and depth of invasion were independent risk factors for lymph node metastasis(P<0.01 and P<0.05). Gender, age, tumor gross pattern, tumor differentiation, carcinoembryonic antigen level, and tumor diameter were not associated with lymph node metastasis. Lymph node metastasis and distant metastasis on postoperative follow-up were independent risk factors for survival(P<0.05 and P<0.01).</p><p><b>CONCLUSION</b>Factors associated with lymph node metastasis in pT1-2 colorectal cancer do not affect the survival. However, lymph node metastasis and distant metastasis are predictive for survival.</p>
Full text:
1
Index:
WPRIM
Main subject:
Pathology
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Prognosis
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Colorectal Neoplasms
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Chi-Square Distribution
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Logistic Models
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Proportional Hazards Models
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Retrospective Studies
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Risk Factors
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Follow-Up Studies
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Diagnosis
Type of study:
Diagnostic_studies
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Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limits:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
Language:
Zh
Journal:
Chinese Journal of Gastrointestinal Surgery
Year:
2011
Type:
Article