Study on the tumor infiltration in mesorectum of rectal cancer by spiral computed tomography and histopathology / 中华外科杂志
Chinese Journal of Surgery
; (12): 599-602, 2009.
Article
in Zh
| WPRIM
| ID: wpr-238875
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the value of spiral computed tomography in the preoperative assessment of the degree of tumor infiltration in mesorectum and circumferential resection margin status of rectal cancer compared with large tissue slice technique.</p><p><b>METHODS</b>Fifty-seven patients with rectal cancer diagnosed by fiber colonoscopy and pathology from March 2007 to December 2007 underwent preoperative 64-layers spiral CT examination. The degree of tumor infiltration in mesorectum and circumferential resection margin status were evaluated. Large tissue slice technique was applied in the pathologic study after the total mesorectal excision of the rectum to determine the degree of tumor infiltration in mesorectum and the circumferential resection margin status. The spiral CT findings were compared with pathologic results. The accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of the CT results were assessed respectively.</p><p><b>RESULTS</b>The overall spiral CT accuracy was 93.0% (53/57) for the degree of tumor infiltration in mesorectum, and it was 94.7%, 94.7% and 96.5% for degree I, II, III infiltration, respectively. Fifty-three cases (93.0%) were accurately predicated with the circumferential resection margin status. The sensitivity, specificity, PPV and NPV of spiral CT measurement was 80.0%, 97.6%, 92.3% and 93.2%, respectively, and was consistent well with the histopathological diagnosis.</p><p><b>CONCLUSIONS</b>Spiral CT provides accurate preoperative assessment for the degree of tumor infiltration in mesorectum and circumferential resection margin status of rectal cancer.</p>
Full text:
1
Index:
WPRIM
Main subject:
Pathology
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Rectal Neoplasms
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Rectum
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Diagnostic Imaging
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Predictive Value of Tests
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Sensitivity and Specificity
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Tomography, Spiral Computed
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Mesentery
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Neoplasm Invasiveness
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Neoplasm Staging
Type of study:
Diagnostic_studies
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Prognostic_studies
Limits:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
Language:
Zh
Journal:
Chinese Journal of Surgery
Year:
2009
Type:
Article