Effect of xuezhikang on blood lipids, serum oxidized low density lipoprotein, C-reactive protein and fibrinogen in patients with unstable angina pectoris / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
; (12): 750-752, 2003.
Article
in Zh
| WPRIM
| ID: wpr-240870
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the lipid regulatory effect of Xuezhikang (XZK) and its effects on serum oxidized low density lipoprotein (OX-LDL), C-reactive protein (CRP) and fibrinogen (FIB) in patients with unstable angina pectoris (UAP).</p><p><b>METHODS</b>UAP patients with hyperlipidemia were treated with XZK 0.6 g, orally taken, twice a day for 2 successive months followed by half dosage for 2 months. To UAP patients with normal blood lipids, Vit E was given orally for 4 months. Levels of blood lipids, OX-LDL, CRP, FIB at the time of entry, 1st and 2nd month of the therapeutic course were observed and end-point events in the two groups was compared.</p><p><b>RESULTS</b>XZK can reduce the serum level of total cholesterol, low density lipoprotein after being administered for 1 month, and the effect further elevated after 2 months. Its effect in lowering triglycerides and increasing high density lipoprotein initiated after 2 months administration. Compared with effect of Vit E, XZK can significantly lower the serum OX-LDL, CRP and FIB after 2 months administration, and reduce the end-point events in 4 months.</p><p><b>CONCLUSION</b>XZK has good regulatory effect on blood lipids, it also can inhibit the development of inflammation in coronary plaque, therefore, is beneficial to the prognosis of UAP patients.</p>
Full text:
1
Index:
WPRIM
Main subject:
Oryza
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Blood
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C-Reactive Protein
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Fibrinogen
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Drugs, Chinese Herbal
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Cholesterol
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Follow-Up Studies
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Therapeutic Uses
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Drug Therapy
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Hyperlipidemias
Type of study:
Observational_studies
/
Prognostic_studies
Limits:
Adult
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Aged
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Female
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Humans
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Male
Language:
Zh
Journal:
Chinese Journal of Integrated Traditional and Western Medicine
Year:
2003
Type:
Article