Expression of Tumor Metastasis Related Genes in Korean Colorectal Cancers and Cell lines
Journal of the Korean Society of Coloproctology
; : 11-19, 1998.
Article
in Ko
| WPRIM
| ID: wpr-24104
Responsible library:
WPRO
ABSTRACT
We studied the expressions of E-cadherin, MMP-7 and CD44V in colorectal cancer and their corresponding normal mucosa using RT-PCR. From the 26 patients whom a com parative study of clinical and histopathological data is available, MMP-7 and CD44V were significantly enhanced in cancer and their metastatic tissues, compared with their normal mucosa. E-cadherin did not reveal any difference between cancer and normal mucosa. The relashionship between these genes and colorectal cancer development can not be confirmed by this study, however CD44v and MMP-7 may be associated with metastasis of colorectal cancer.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Colorectal Neoplasms
/
Cadherins
/
Cell Line
/
Mucous Membrane
/
Neoplasm Metastasis
Limits:
Humans
Language:
Ko
Journal:
Journal of the Korean Society of Coloproctology
Year:
1998
Type:
Article