A large-scale survey for rare blood group screening among blood donors in Chinese over Nanjing area / 中国实验血液学杂志
Journal of Experimental Hematology
; (6): 231-234, 2011.
Article
in Zh
| WPRIM
| ID: wpr-244948
Responsible library:
WPRO
ABSTRACT
The purpose of this study was to investigate the distribution of 10 rare red blood groups in Chinese Nanjing population, so as to provide compatible rare blood to patients and to create a donor data bank. Jk (a-b-) (Kidd) phenotypes were detected by urea, while H-(H), GPA-(MNS), GPC-(Gerbich), i+ (Ii) and Lub-(Lutheran) phenotypes were detected by monoclonal, polyclonal antibodies with U type 96 well microplate technology. The screening of Jsb- and k-(Kell), Fya-(Duffy), Ok-(Ok), s-(MNS) and Dib-(Digeo) phenotypes were performed by polymerase chain reaction. The results showed that 2 Jk (a-b-) out of 40337 donation samples and 3 Fy (a-b+) out of 1782 donation samples were found, while no other rare blood phenotypes (H-, GPA-, GPC-, Lub-, Ok-, s-, Jsb-, k-, Dib- and i+) were detected. It is concluded that the frequencies of Jk (a-b-) and Fya(a-b+) are 0.0049% and 0.168% respectively. No more rare blood phenotype was found in this screening.
Full text:
1
Index:
WPRIM
Main subject:
Phenotype
/
Blood Group Antigens
/
Blood Grouping and Crossmatching
/
Classification
/
Cell Biology
/
Asian People
/
Erythrocytes
/
Genetics
Type of study:
Diagnostic_studies
/
Screening_studies
Limits:
Humans
Language:
Zh
Journal:
Journal of Experimental Hematology
Year:
2011
Type:
Article