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The significance of No.13 lymph node dissection in D2 gastrectomy for lower-third advanced gastric cancer / 中华外科杂志
Chinese Journal of Surgery ; (12): 235-239, 2013.
Article in Chinese | WPRIM | ID: wpr-247860
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the feasibility and necessity of No.13 lymph node dissection in D2 radical gastrectomy for lower-third advanced gastric cancer (AGC).</p><p><b>METHODS</b>Data of 379 cases who were diagnosed as TNM II-III stage AGC were collected from January 2001 to June 2007. One hundred cases who undergone No.13 lymph node dissection during D2 gastrectomy for lower-third AGC were selected as study group. Other 279 cases (control group) received only D2 gastrectomy. The differences in clinicopathologic and intraoperative and postoperative parameters and 5-years survival rate were compared using the SPSS 17.0 software.</p><p><b>RESULTS</b>There were no significant differences between the two groups in patients' gender, age, tumor size, histologic type, Borrmann type, duodenum invasion, tumor depth, lymph node metastasis, TNM classification, operative time, blood loss and the incidence of postoperative complications (P > 0.05). In the study group, there were 9 patients with positive No. 13 lymph node, and its 5-year survival rate (46.0%) was higher than the control group (36.5%, χ² = 4.452, P < 0.05). The Univariate analysis showed that age (χ² = 7.539), No.13 lymph node dissection (χ² = 4.452), tumor size (χ² = 7.100), duodenum invasion (χ² = 9.106), tumor depth (χ² = 7.428), lymph node metastasis (χ² = 45.046), TNM classification (χ² = 57.008) are associated with prognosis of lower-third AGC (P < 0.05). Multivariate analysis identified age (HR = 0.500, 95% CI 0.343 - 0.730), tumor size (HR = 0.545, 95%CI 0.339 - 0.876), duodenum invasion (HR = 5.821, 95%CI 2.326 - 14.572), and tumor depth (T4 HR = 2.087, 95% CI 1.283 - 3.394) as independent prognostic factors (P < 0.05).</p><p><b>CONCLUSION</b>No. 13 lymph node dissection for TNM II-III stage lower-third advanced gastric cancer is feasible and necessary.</p>
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Pathology / Stomach Neoplasms / General Surgery / Multivariate Analysis / Survival Rate / Risk Factors / Mortality / Gastrectomy / Lymph Node Excision Type of study: Etiology study / Prognostic study / Risk factors Limits: Adult / Aged / Aged80 / Female / Humans / Male Language: Chinese Journal: Chinese Journal of Surgery Year: 2013 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pathology / Stomach Neoplasms / General Surgery / Multivariate Analysis / Survival Rate / Risk Factors / Mortality / Gastrectomy / Lymph Node Excision Type of study: Etiology study / Prognostic study / Risk factors Limits: Adult / Aged / Aged80 / Female / Humans / Male Language: Chinese Journal: Chinese Journal of Surgery Year: 2013 Type: Article