Acute transverse myelitis associated with coxsackievirus B---A retrospective analysis of 7 patients / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
; (6): 60-62, 2008.
Article
in Zh
| WPRIM
| ID: wpr-254140
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>Acute Transverse myelitis (ATM) is a focal inflammatory disorder of the spinal cord, resulting in motor, sensory, and autonomic nerve dysfunction. There is often a clearly defined rostral border of sensory dysfunction. Nowadays, the pathogenesis of ATM is not clear. The present study aimed to understand possible relationship between ATM and infection with Coxsackievirus B.</p><p><b>METHODS</b>IgM antibody against Coxsackievirus B was detected in cerebrospinal fluid of 33 patients with ATM.</p><p><b>RESULTS</b>In 7 of the 33 cases with ATM, the IgM andtibody Coxsackievirus B (CVB) was positive. No infections with other pathogens were found at the onset of the disease.</p><p><b>CONCLUSION</b>The pathogenesis of ATM may involve infection with Coxsackievirus B.</p>
Full text:
1
Index:
WPRIM
Main subject:
Pathology
/
Physiology
/
Virology
/
Virulence
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Immunoglobulin M
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Cerebrospinal Fluid
/
Retrospective Studies
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Enterovirus B, Human
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Allergy and Immunology
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Antibodies, Viral
Type of study:
Observational_studies
/
Risk_factors_studies
Limits:
Adult
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Female
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Humans
/
Male
Language:
Zh
Journal:
Chinese Journal of Experimental and Clinical Virology
Year:
2008
Type:
Article