Regulatory Effects of Long Non-coding RNA on Tumorigenesis / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 358-363, 2015.
Article
in English
| WPRIM
| ID: wpr-257628
ABSTRACT
Long non-coding RNAs(LncRNA)may play a key role in tumorigenesis by regulating gene expression and intervening transcription. Recent studies have demonstrated that a series of patterns including protein modification,chromosomal reconstruction,regulation of target gene expression,transcription intervention,epigenetic modification,and natural antisense transcript are involved in this process. This article reviews recent research advances in this aspect with an attempt to better understand the role of LncRNA in tumorigenesis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Gene Expression Regulation, Neoplastic
/
Cell Transformation, Neoplastic
/
Epigenesis, Genetic
/
RNA, Long Noncoding
Limits:
Humans
Language:
English
Journal:
Acta Academiae Medicinae Sinicae
Year:
2015
Type:
Article
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