Effect of Jiangzhi Kangyanghua mixture on high-sensitivity C-reactive protein and vascular endothelial functions of hypertension patients / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 3583-3586, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-291322
ABSTRACT
To observe the effect of Jiangzhikangyanghua Mixture on high-sensitivity CRP (hs-CRP) and vascular endothelial functions of essential hypertension (EH) patients. In this study, 72 cases of out-patients with EH were selected from department of cardiology of Wujin hospital of traditional Chinese Medicine, and randomly divided into the control group (n= 36, amlodipine 5 mg qd + valsartan 80 mg qd) and the test group (n =36 amlodipine 5 mg qd + valsartan 80 mg qd + Jiangzhikangyanghua mixture 20 mL tid). The contents of hs-CRP, ET-1 and NO were measured before and after treatment for two months. The result showed that the contents of hs-CRP, ET-1 in both groups reduced (P <0. 05) , while the test group show a more significant reduction than the control group (P <0. 05). After the treatment, the content of NO raised in both group, while the test group show a more significant increase than that of the control group (P <0. 05). This study indicated that Jiangzhi Kangyanghua mixture could reduce the contents of hs-CRP and ET-1 and raise NO of EH patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Blood Pressure
/
C-Reactive Protein
/
Drugs, Chinese Herbal
/
Endothelium, Vascular
/
Endothelin-1
/
Drug Therapy
/
Hypertension
/
Metabolism
/
Antihypertensive Agents
Type of study:
Diagnostic study
Limits:
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2013
Type:
Article
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