Modified Jujing No.2 Decoction for varicocele-induced male infertility / 中华男科学杂志
National Journal of Andrology
;
(12): 645-648, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-304696
ABSTRACT
<p><b>Objective</b>To investigate the clinical effect of Jujing No.2 Decoction on male infertility induced by varicocele.</p><p><b>METHODS</b>We equally randomized 70 male patients with varicocele-induced infertility into a treatment group and a control group, the former treated with modified Jujing No.2 Decoction (1 dose a day, bid) and the latter given Danshen Tablets (4 tablets once, tid) plus Liu Wei Di Huang Wan (8 pills once, tid), both for 3 months. We examined the spermatic veins of the patients by ultrasonography and performed seminal analysis before and after medication.</p><p><b>RESULTS</b>Compared with the controls, the patients in the treatment group showed significant improvement after medication in sperm concentration ([12.35±2.12] vs [18.56±4.16] ×10⁶/ml, P<0.05), progressively motile sperm ([16.18±6.34] vs [24.63±8.51] %, P<0.05), and morphologically normal sperm ([11.59±5.31] vs [14.17±6.02] %, P<0.05). In the control group, sperm concentration was increased from (12.29±2.07) ×10⁶/ml at the baseline to (13.13±3.13) ×10⁶/ml after medication, progressively motile sperm from (16.13±6.45) % to (20.55±7.30) % (P<0.05), and morphologically normal sperm from (11.62±5.35) % to (12.69±5.77) %. The total effectiveness rate was significantly higher in the treatment than in the control group (71.88% vs 46.67%, P<0.05). The inner diameter of the left spermatic vein was decreased from (0.32±0.05) mm at the baseline to [0.26±0.05] mm after medication in the treatment group (P<0.05) and from (0.32±0.03) mm to (0.29±0.04) mm in the control (P<0.05), with statistically significant difference between the two groups after medication (P<0.05).</p><p><b>CONCLUSIONS</b>Jujing No.2 Decoction is effective in the treatment of varicocele-induced male infertility.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Sperm Count
/
Sperm Motility
/
Spermatic Cord
/
Varicocele
/
Veins
/
Diagnostic Imaging
/
Drugs, Chinese Herbal
/
Therapeutic Uses
/
Drug Therapy
/
Infertility, Male
Type of study:
Controlled clinical trial
/
Diagnostic study
Limits:
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2016
Type:
Article
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