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Relationship between epigenetics of sperm and embryogenesis / 中华男科学杂志
National Journal of Andrology ; (12): 734-737, 2014.
Article in Chinese | WPRIM | ID: wpr-309646
ABSTRACT
Epigenetics comprises the modifications made in gene expressions without changing the DNA sequence itself. Significant epigenetic changes take place during spermatogenesis and fertilization and exert direct influences on embryogenesis. This article provides an overview of the latest researches on epigenetics of male germ cells and a brief discussion on the correlation of sperm with embryogenesis in four aspects DNA methylation, histone modification, regulation of non-coding RNAs, and genomic imprinting.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Spermatozoa / Histones / Genomic Imprinting / DNA Methylation / Epigenesis, Genetic / Embryonic Development / Metabolism Limits: Animals / Humans / Male Language: Chinese Journal: National Journal of Andrology Year: 2014 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Spermatozoa / Histones / Genomic Imprinting / DNA Methylation / Epigenesis, Genetic / Embryonic Development / Metabolism Limits: Animals / Humans / Male Language: Chinese Journal: National Journal of Andrology Year: 2014 Type: Article