Influence of sperm DNA damage on reproductive outcomes and its clinical significance / 中华男科学杂志

ABSTRACT

Many factors are responsible for sperm DNA damage, which may lead to fertilization failure and embryo maldevelopment. At present, sperm DNA damage can be detected by more and more methods, which are considered to be superior to the conventional measures. There are some clinical indications for tests of sperm DNA damage in IVF/ICSI, but additional studies are still needed to fully define the clinical value of testing sperm DNA damage.