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Prognostic analysis of 280 patients with T4a gastric cancer who underwent curative resection / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery ; (12): 1261-1264, 2012.
Article in Chinese | WPRIM | ID: wpr-312311
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the predicators of survival and recurrence after curative resection for gastric cancer patients with serosal invasion.</p><p><b>METHODS</b>Clinical and follow-up data of 280 patients with T4a gastric cancer(according to the 7th UICC TNM Classification for gastric cancer) who underwent curative resection for gastric cancer between January 1997 and December 2003 were analyzed retrospectively.</p><p><b>RESULTS</b>Five-year survival rate of these 280 patients was 50.0% and 158 patients (56.4%) presented with recurrence after surgery. The 3-year disease-free survival rate was 57.5%. The number of lymph node metastasis and metastatic lymph node ratio(MLR) were identified as the independent predicators for overall survival(P<0.05). The extent of lymph node metastasis was identified as the independent predicators for disease free survival (P<0.05). The extent of lymph node metastasis, the number of lymph node metastasis, and MLR were identified as the independent predicators for recurrence after surgery(P<0.05).</p><p><b>CONCLUSIONS</b>The number of lymph node metastases, extent of lymph node metastasis and MLR are independent predictors of overall survival and recurrence in T4a gastric cancer patients after curative resection.</p>
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Prognosis / Stomach Neoplasms / General Surgery / Survival Rate / Retrospective Studies / Disease-Free Survival / Diagnosis / Gastrectomy / Lymphatic Metastasis / Neoplasm Recurrence, Local Type of study: Diagnostic study / Observational study / Prognostic study Limits: Humans Language: Chinese Journal: Chinese Journal of Gastrointestinal Surgery Year: 2012 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Prognosis / Stomach Neoplasms / General Surgery / Survival Rate / Retrospective Studies / Disease-Free Survival / Diagnosis / Gastrectomy / Lymphatic Metastasis / Neoplasm Recurrence, Local Type of study: Diagnostic study / Observational study / Prognostic study Limits: Humans Language: Chinese Journal: Chinese Journal of Gastrointestinal Surgery Year: 2012 Type: Article