Your browser doesn't support javascript.
loading
Dietary exposure of the Chinese population to acrylamide / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences ; (12): 421-429, 2013.
Article in English | WPRIM | ID: wpr-320322
ABSTRACT
<p><b>OBJECTIVE</b>To assess the current status of the acrylamide in the Chinese food supply, the dietary acrylamide exposure in the Chinese population and to estimate the public health risks of the current consumption.</p><p><b>METHODS</b>The acrylamide content in the total diet study (TDS) food samples was analyzed using an LC-MS/MS method. Based on the analytical results, the dietary exposure calculations were performed using a deterministic method, combining mean acrylamide concentrations from the food group composite with their associated food consumptions.</p><p><b>RESULTS</b>Acrylamide was detected in 43.7% of all samples collected and acrylamide concentration varied from ND to 526.6 µg/kg. The estimated dietary intakes of acrylamide among Chinese general population given as the mean and the 95th percentile (P95) were 0.286 and 0.490 µg•kg(-1) bw•day(-1), respectively. The margins of exposure (MOEs) for the population calculated using both benchmark dose lower confidence limit for a 10% extra risk of tumors in animals (BMDL10) 0.31 and 0.18 µg•kg(-1) bw•day(-1), were 1069 and 621 for the mean dietary exposure, and 633 and 367 for the high dietary exposure respectively.</p><p><b>CONCLUSION</b>These MOE values might indicate a human health concern on acrylamide for Chinese population. Efforts should continue to reduce acrylamide levels in food in order to reduce the dietary risks to the human health.</p>
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Food Contamination / Chemistry / China / Acrylamide / Diet / Environmental Exposure / Environmental Pollutants / Food Analysis Limits: Humans Country/Region as subject: Asia Language: English Journal: Biomedical and Environmental Sciences Year: 2013 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Main subject: Food Contamination / Chemistry / China / Acrylamide / Diet / Environmental Exposure / Environmental Pollutants / Food Analysis Limits: Humans Country/Region as subject: Asia Language: English Journal: Biomedical and Environmental Sciences Year: 2013 Type: Article