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Influence of diethyl sulfate (DES) mutagenesis on growth properties and pigment secondary metabolites of Phellinus igniarius / 中国中药杂志
China Journal of Chinese Materia Medica ; (24): 2293-2298, 2015.
Article in Chinese | WPRIM | ID: wpr-337942
ABSTRACT
The diethyl sulfate (DES) mutagenesis was chosen for the mutagenic treatment to Phellinus igniarius, and the relationship of mutagenesis time and death rate was investigated with 0.5% DES. The differences of mycelial growth speed, liquid fermentation mycelia biomass, morphology and pigment classes of secondary metabolites production speed and antioxidant activities of metabolite products were discussed. The study displayed that DES mutagenesis could change mycelial morphology without obvious effect on mycelium growth, and the DES mutagenesis improved antioxidant activities of the active ingredients of P. igniarius and had more antioxidant activity of hypoxia/sugar PC12 nerve cells than that of P. igniarius.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Pharmacology / Pigments, Biological / Sulfuric Acid Esters / Basidiomycota / Mutagenesis / Mycelium / Secondary Metabolism / Genetics / Metabolism / Mutagens Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2015 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pharmacology / Pigments, Biological / Sulfuric Acid Esters / Basidiomycota / Mutagenesis / Mycelium / Secondary Metabolism / Genetics / Metabolism / Mutagens Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2015 Type: Article