Treatment of non-alcoholic fatty liver disease by Qianggan Capsule / 中国结合医学杂志
Chinese journal of integrative medicine
; (12): 23-27, 2010.
Article
in En
| WPRIM
| ID: wpr-344953
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To observe the therapeutic effect and safety of Qianggan Capsule (QGC) in treating non-alcoholic fatty liver disease (NAFLD), using polyene phosphatidylcholine capsule (PPC) as a reference.</p><p><b>METHODS</b>Eighty-eight patients with NAFLD were randomly assigned to two groups, 45 in the treatment group treated with QGC and 43 in the control group treated with PPC. The course of treatment lasted for 6 months. Changes in liver function, blood lipids, and iconographic indexes before and after treatment were observed, and clinical efficacy was evaluated.</p><p><b>RESULTS</b>In the treatment group, alanine aminotransferase (ALT) was lowered significantly from 56.02 + or - 32.59 IU/L before treatment to 38.27 + or - 22.68 IU/L after treatment, and CT liver/spleen ratio significantly increased from 0.69 + or - 0.18 to 0.91 + or - 0.25, showing statistical significance (P<0.05); in contrast, the corresponding changes of the two indexes in the control group were 56.56 + or - 26.33 IU/L to 49.67 + or - 26.22 IU/L, and 0.66 + or - 0.20 to 0.75 + or - 0.24, respectively, the pre-post treatment difference showing insignificant difference (P>0.05). No severe adverse reactions occurred during the whole treatment course.</p><p><b>CONCLUSION</b>QGC is an effective and safe remedy for the treatment of NAFLD.</p>
Full text:
1
Index:
WPRIM
Main subject:
Blood
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Capsules
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Diagnostic Imaging
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Drugs, Chinese Herbal
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Biomarkers
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Tomography, X-Ray Computed
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Treatment Outcome
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Alanine Transaminase
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Drug Therapy
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Fatty Liver
Type of study:
Diagnostic_studies
Limits:
Adolescent
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Adult
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Female
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Humans
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Male
Language:
En
Journal:
Chinese journal of integrative medicine
Year:
2010
Type:
Article