Study on antioxidant effect and chemical constituents of taohong siwu decoction / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 1591-1595, 2011.
Article
in Zh
| WPRIM
| ID: wpr-354198
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WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the antioxidant effects of Taohong Siwu decoction and to exploit the bioactive constituents.</p><p><b>METHOD</b>The samples were prepared by macroporous adsorptive resins (TH-1-TH-15). Three antioxidant models were adopted to evaluate the antioxidant activities of Taohong Siwu decoction and its different separated fractions in vitro. It was found that fractions (TH-2, TH-4, TH-7, TH-8, TH-9), separated from Taohong Siwu decoction, mainly contributed to the antioxidant effects. The chemical constituents in the most active fraction TH-8 were identified and determined by HPLC.</p><p><b>RESULT</b>TH-8 showed significant antioxidant activities in the antioxidant experiments. Six compounds in the fraction were determined which were amygdalin, albiflorin, paeoniflorin, benzoic acid, coumaric acid and ferulic acid. The contents were 75.70, 31.26, 60.79, 1.196, 1.108, 4.861 mg L(-1), respectively.</p><p><b>CONCLUSION</b>Glycosides and aromatic acids may be the principle effective constituents in the active fraction.</p>
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Index:
WPRIM
Main subject:
Drugs, Chinese Herbal
/
Chemistry
/
Antioxidants
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2011
Type:
Article