Advances in the study of signal transduction in cavernous smooth muscle / 中华男科学杂志
National Journal of Andrology
; (12): 130-133, 2004.
Article
in Zh
| WPRIM
| ID: wpr-357065
Responsible library:
WPRO
ABSTRACT
The signal transduction pathways within corporal smooth muscle cells are the intracellular molecular mechanisms of corporal smooth muscle tone regulation. Various neurotransmitters activate the membrane receptor proteins or intracellular enzyme pathways and result in the production of extracellular chemical signals. Second messenger molecules and ions transmit and amplify the signals, and subsequently induce the relaxation of smooth muscle cells and penile erection. Therefore, the study of signal transduction in cavernous smooth muscle play an important role in understanding the physiology of erection and the pathophysiology of erectile dysfunction as well as in developing new selective drugs for the treatment of erectile dysfunction.
Full text:
1
Index:
WPRIM
Main subject:
Penis
/
Physiology
/
Myosin-Light-Chain Kinase
/
Signal Transduction
/
Calcium
/
Metabolism
/
Muscle, Smooth
Limits:
Humans
/
Male
Language:
Zh
Journal:
National Journal of Andrology
Year:
2004
Type:
Article