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Role of Neutrophils in Ischemia/Reperfusion Injury during Heart Surgery / 日本心臓血管外科学会雑誌
Japanese Journal of Cardiovascular Surgery ; : 8-11, 2002.
Article in Japanese | WPRIM | ID: wpr-366738
ABSTRACT
To test the hypothesis that neutrophils play a role in ischemia/reperfusion injury during heart surgery, granulocyte elastase and myeloperoxidase release from coronary circulation were measured before and after aortic cross-clamping. The production of granulocyte elastase and myeloperoxidase across the coronary circulation elevated significantly after release of aortic cross-clamp. Furthermore, the level of granulocyte elastase and myeloperoxidase released from coronary circulation demonstrated positive correlation with the duration of the aortic cross-clamp. These data indicate that neutrophils play a major role in ischemia/reperfusion injury occurring during heart surgery.
Full text: Available Index: WPRIM (Western Pacific) Language: Japanese Journal: Japanese Journal of Cardiovascular Surgery Year: 2002 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Japanese Journal: Japanese Journal of Cardiovascular Surgery Year: 2002 Type: Article