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Malignant Hyperthermia after Surgical Repair of Acute Type A Aortic Dissection / 日本心臓血管外科学会雑誌
Article in Ja | WPRIM | ID: wpr-367074
Responsible library: WPRO
ABSTRACT
A 45-year-old man underwent total arch replacement for acute type A aortic dissection. Vital signs during the operation remained stable, but sinus tachycardia was recognized about 7h postoperatively, followed by a high level of PaCO<sub>2</sub>, low level of PaO<sub>2</sub> and metabolic acidosis. Then, blood pressure decreased, accompanied rapid elevation of body temperature to 39.7°C. Body temperature was decreased gradually by cooling the whole body, however, coma, anuria and hypoxemia persisted. A diagnosis of malignant hyperthermia was made and Dantrolene was administered. However, the patient died of multiple organ failure 7 days postoperatively. The serum level of CPK increased to 12, 446IU/<i>l</i> and serum myoglobin elevated to a very high level (36, 500ng/ml) 2 days postoperatively. Although, it is very rare for malignant hyperthermia to develop after open-heart surgery, physicians must keep this disease in mind if sudden hyperthermia of unknown origin is demonstrated.
Full text: 1 Index: WPRIM Language: Ja Journal: Japanese Journal of Cardiovascular Surgery Year: 2005 Type: Article
Full text: 1 Index: WPRIM Language: Ja Journal: Japanese Journal of Cardiovascular Surgery Year: 2005 Type: Article