Collagen Gel Droplet-Embedded Culture Drug Sensitivity Test (CD-DST) for a Leiomyosarcoma Originating in the Inferior Vena Cava / 日本心臓血管外科学会雑誌
Japanese Journal of Cardiovascular Surgery
; : 124-127, 2013.
Article
in Ja
| WPRIM
| ID: wpr-374393
Responsible library:
WPRO
ABSTRACT
The collagen gel droplet-embedded culture drug sensitivity test (CD-DST) identifies effective anticancer drug using resected tumor specimen, enabling tailor-made chemotherapy for a rare tumor. We report a case of the patient with leiomyosarcoma originating in the inferior vena cava, to which CD-DST was applied. This application has not been previously reported to the best of our knowledge. A 61-year-old woman consulted a nearby hospital because of abdominal pain. Computed tomography revealed an inferior vena cava tumor. The tumor was resected with the inferior vena cava, which was reconstructed with a 16 mm ePTFE graft. The tumor was diagnosed as leiomyosarcoma histopathologically. CDDP, VP-16, ADR, and VDS were CD-DST showed the tumor to be sensitive. Her postoperative course has been good without recurrence of tumor for 6 months, and the results of CD-DST may be helpful for chemotherapy strategy in case of recurrence.
Full text:
1
Index:
WPRIM
Type of study:
Diagnostic_studies
Language:
Ja
Journal:
Japanese Journal of Cardiovascular Surgery
Year:
2013
Type:
Article