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Observing hemodynamic changes in the spinal cord after acute spinal cord injury / 中华物理医学与康复杂志
Chinese Journal of Physical Medicine and Rehabilitation ; (12): 581-585, 2009.
Article in Chinese | WPRIM | ID: wpr-380442
ABSTRACT
Objective To observe any changes in spinal cord hemodynamics after spinal cord injury and to investigate their mechanism. Methods Twenty female Sprague-Dawley rats were divided into a control group and a moderate injury group,10 rats in each group.A rat model of spinal cord injury caused by moderate compression was established using Nystrom's method.Changes in the velocity and volume of blood flow and in the diameters of vessels of the spinal cord were monitored for 6 hours using laser speckle imaging. Results No changes in the velocity or volume of blood flow or in the diameter of vessels were observed in the control group,but all of these indices diminished significantly in the injury group. Conclusions Laser speckle imaging can be used to monitor changes in spinal cord hemodynamics.Such changes after acute spinal cord injury indicate progressive post-injury ischemia.The occlusion of veins may be an important contributor to post-injury ischemia.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Physical Medicine and Rehabilitation Year: 2009 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Physical Medicine and Rehabilitation Year: 2009 Type: Article