Quantification and genotyping of PCV2 DNA in the tissues of PCV2-infected conventional pigs with different clinical signs / 대한수의학회지
Korean Journal of Veterinary Research
;
: 7-14, 2011.
Article
in English
| WPRIM
| ID: wpr-38065
ABSTRACT
This study was focused on the genotyping and quantification of Porcine circovirus type 2 (PCV2) in thirty PCV2-positive pigs with different clinical symptoms (PCV2-infected without wasting, PCV2-infected with wasting, PCV2-infected with wasting and lymphoid depletion). The quantity of PCV2 DNA in diverse tissues was significantly differed among these groups. (One-way ANOVA test, p < 0.001) Interestingly, PCV2-DNA load in tissues of PCV2-infected pigs without wasting and PCV2-infected pigs with wasting and lymphoid depletion were not significantly differed (p = 0.38), while they were all significantly higher when compared with PCV2-infected pigs with wasting-only. PCV2 DNA quantity in tissues was significantly higher in PCV2a and 2b co-infected pigs compared to the PCV2b only-infected pigs (Wilcoxon test, p = 0.039). The PCV2a and 2b co-infected pigs had increased wasting and lymphoid depletion rate but it was not statistically significant. Therefore, this cross-sectional study suggested that PCV2 DNA load in tissues was diverse by clinical and histological findings. Furthermore, co-infection of PCV2a and 2b affected to the PCV2 DNA load in tissues with increased rate of wasting and lymphoid depletion.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Swine
/
DNA
/
Cross-Sectional Studies
/
Circovirus
/
Coinfection
/
Genotype
Type of study:
Diagnostic study
/
Observational study
/
Prevalence study
/
Risk factors
Language:
English
Journal:
Korean Journal of Veterinary Research
Year:
2011
Type:
Article
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