Efficacy of three dimensional conformal radiotherapy combined with transcatheter arterial chemoembolization on primary hepatocellular carcinoma / 中国基层医药

ABSTRACT

Objective To evaluate the effect of hepatic arterial chemo-embolization( TACE) combined threedimensional conformal radiation therapy (3 D-CRT) in treatment of un- resectable primary hepatocellular cancer (PHC). Methods 80 patients with PHC were divided into TACE therapy(control group) 40 cases and 3D-CRT + TACE treatment( observation group)40 cases,The efficacy and survival rate was observed. Results The rate of effect in observation group were 35 cases (87. 5% ) higher than that 28 cases (70. 0% ) in control group ( x2 = 3. 89, P < 0.05 ) ,The rate of survival in observation group of 1、2、3-year were 67. 5% ,55. 5% ,40. 0% which were higher than that 50. 0% ,27. 5% ,15. 0% in control group( x2 = 3.4576, x2= 3.726, x2 = 3. 635, all P < 0.05), The incidence of adverse reactions in two groups had no significant difference ( P <0.05). Conclusion The three-dimensional conformal radiotherapy combined with transcatheter arterial chemoem-bolization for unresectable primary hepatocellular cancer had a better efficacy,and adverse reactions could be tolerated.