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Advance in research of CDX2 and CDH17 in gastric cancer / 国际外科学杂志
International Journal of Surgery ; (12): 831-834, 2009.
Article in Chinese | WPRIM | ID: wpr-392081
ABSTRACT
Caudal-related homeobox transcription factor CDX2 is a specific nuclear transcription factor. It seems to play a key role in intestinal development and differentiation in normal and cancer tissues, and it is important for the maintenance of intestinal epithelium cells, liver-intestine cadherin(CDHIT) as one protein has intimate correlation with invasion and metastasis of tumor, has as well as highly expresses in intestinal-mucosa. Recent studies indicate that CDX2 and CDHI7 is closely associated with tumorigenesis,differentia-tion and metastasis. They might act as a new biomarker of gastric cancer diagnosis and a new target of tumor gene therapy.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: International Journal of Surgery Year: 2009 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: International Journal of Surgery Year: 2009 Type: Article