Study on allergy to medications in staff of Bach Mai Hospital

ABSTRACT

Allergic reactions to medications are increasing not only in patients but also in medical practitioner. Objectives: 1) Finding out prevalence of drug allergy in Bach Mai hospital staffs and listed medications caused allergic reactions. 2) Comparison some aspects of drug allergy between the health staffs and other groups. 3, Study on clinical symptoms of drug allergy and bring forward views. Subjects: 215 physicians, pharmacists, nurses, techniciants of Bach Mai Hospital and 200 staffs with other jobs. Method: Cross-sectional comparative surveys. Results: The prevalence of allergic reaction in health staffs is higher and these ones had more likely to have drug allergy by 2.5 times compared with other occupational groups. Almost all medications used in clinical practice can cause allergic reactions to the health staffs. Antibiotics were major cause and allergic reactions to familiar beta-lactams happened in the health staffs via contact. Main clinical symptoms of drug allergy were urticaria, prurigo, vomitting, nause and erythema with 3 main syndromes: urticaria, quincke edema and allergic dermatitis. Allergic reactions in health staffs of hospital are needed to pay more attention. Conclusion: the prevalence of drug allergy in Bach Mai Hospital staffs is high and these subjects should be protected from this condition.