Biological and biomechanical properties of reconstructing anterior cruciate ligament of knee joint / 中国组织工程研究

ABSTRACT

OBJECTIVE: To probe into the function of early exercises on healing of grafts after anterior cruciate ligament (ACL) reconstruction and on motor function recovery of knee joint by summarizing biology and biomechanical properties of ACL reconstruction.DATA SOURCES: The relevant literatures on ACL reconstruction of knee joint and its biomechanical properties were looked up in period of MEDLINE1970-01/2004-01 on computer. Retrieval words: "anterior cruciate ligament, knee joint, biomechanics" only in English.STUDY SELECTION: In initial examination, the complete contents of literatures on ACL reconstruction of knee joint and its biomechanical properties were selected. The controlled papers were randomized, for those written by the same writer, the papers with the most cases were included.Comprehensive and Mete analyzed papers were excluded. Quality evaluation was mainly based on the reality of observed data and rigor of investigation and application.DATA EXTRACTION: Fourty-six papers on ACL reconstruction of knee joint and its biomechanical properties were looked up totally, of which, 29papers were tallied with inclusive criteria, 17 papers were excluded, 9 papers were the analysis on small samples and 8 papers referred to comprehensive and Meta analysis.DATA SYNTHESIS: By understanding biomechanical properties of normal ACL it is to implement reconstruction measures and plan for rehabilitation. Animal experiment after ACL reconstruction suggests that the motor function recovery of knee joint is not satisfactory, but the results of human experiment are superior to animal one. It is indicated in randomized control experiment that immediate weightbearing right after ACL reconstruction will not aggravate knee joint laxity; on the contrary, it is advantageous to alleviate patellar pain.CONCLUSION: Reconstruction of injured ACL fixes knee joints, limits peripheral muscle contraction and results in limited motor function of ligaments, joints and peripheral muscles. Early rehabilitation exercises may alleviate pain, improve articular cartilage metabolism, prevent capsule contracture and benefit recovery of motor function after ACL reconstruction of knee joint.In randomized comparisons of Bear[27], Fischer[28] and Beynnon[29],there is no difference between rehabilitation at home and in hospital after ACL reconstruction with bone-patellar-bone graft.