Improving the diagnosis and treatment of biliary malignant tumor / 中国普通外科杂志

ABSTRACT

Objective　To evaluate the methods for the diagnosis and treatment of biliary malignant tumor(BMT) so as to achieve improvement. Methods　Various methods of diagnosis and treatment of BMT were comprehensively analysed and evaluated. Results and Conclusion　The present laboratory examinations do not show obvious help for the early diagnosis of BMT. Both bile cytology and neoplasm histology may define the character of tumor but the positive rate is low. Although imaging examinations have difficulty in finding early tumor, it may help to define the position, size, infiltration and metastasis of the neoplasm. To diagnose the tumor in its early stage, the monitor and management of some diseases related to BMT should be enhanced, and tumor markers with high susceptibility and specificity should be explored. Operation is the major choice treatment. For advanced neoplasm patients, radical operation or extented radical operation can bring great help for some cases. Palliative surgery may be performed on the patients unable to accept radical operation, and biliary drainage may be performed on the unresectable tumor. The application of special surgery apparatus, such as Peng's Multifunctional Operative Dissector(PMOD), may increase the resection rate of tumor and lymph nodules. Radiotherapy and chemotherapy need further exploration. Gene therapy may likely bring about new hope for the treatment of BMT in the future.