Perioperative management of glucose during open-heart surgery in children / 国际儿科学杂志

ABSTRACT

The perioperative management of blood glucose has been controversial since clinical associations between hyperglycemia and adverse outcomes were fhrst reported.Many studies have demonstrated that hyperglycemia is a universal phenomenon in adults admitted to the ICU and it has been associated with increased morbidity and mortality,additionally,tight glycemic control with intensive insulin therapy in critically ill patients,including cardiac operation patients,significantly improves outcomes.But children's glycometabolism is different from adults',especially the ones who receive open-heart surgery with cardiopulmonary bypass for congenital heart disease,their internal enviroment chang a lot during pedoperative period,and whether hyperglycemia is associated with adverse outcomes after surgery and strict glycemic control is needed are still debatable in critically ill children.Although there are much dispute about perioperative management of glucose during openheart surgery in children,relevant researches are very limited,so further randomized controlled clinical trials are needed.