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Prilimanary investigation of commence time of liver specific phase on Sonazoid contrast-enhanced ultrasound / 中华超声影像学杂志
Chinese Journal of Ultrasonography ; (12): 888-892, 2012.
Article in Chinese | WPRIM | ID: wpr-423558
ABSTRACT
Objective To investigate commence time of liver specific phase on Sonazoid contrastenhanced ultrasound.Methods Rats were administrated with saline (n =6),SonoVue (n =24) and Sonazoid(n =24),respectively.Liver perfusion was performed at 2 min,5 min,10 min and 20 min in situ.Changes of liver enhancement caused by perfusion were quantitatively analyzed.Results Degree of liver enhancement without administration of contrast agent increased after perfusion.In SonoVue group,liver enhancement decreased after perfusion at 2 min and 5 min and increased at 10 min and 20 min significantly.In Sonazoid group,liver enhancement decreased dramatically at 2 min after perfusion,but no changes were found at 5 min,10 min and 20 min after perfusion.Conclusions Liver specific phase on Sonazoid CEUS can begin as early as 5min after administration of contrast agent.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Ultrasonography Year: 2012 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Ultrasonography Year: 2012 Type: Article