The relationship between T lymphocyte subsets and hepatitis B reactivation after chemotherapy / 中国基层医药
Chinese Journal of Primary Medicine and Pharmacy
;
(12): 170-171, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-444208
ABSTRACT
Objective To explore the changes ofT lymphocyte subsets CD3+,CD4+,CD8+ in hepatitis B reactivation after chemotherapy.Methods Flow cytometry was used to detect T lymphocyte subsets of 32 patients with hepatitis B reactivation before and after chemotherapy.In addition,25 patients without hepatitis B reactivition were chosen as control group.Results After chemotherapy,the percentage of CD3+ and CD4+ T lymphocytes and the ratio of CD4+/CDs+ were significantly reduced than those before chemotherapy (P < 0.05).However,the percentage of CD8+ T lymphocytes was not significantly changed(P > 0.05).Conclusion The chemotherapy can change the number and ratio of T lymphocyte subsets,the inhibition of the cellular immune function is one of the reason of hepatitis B virus reactivation.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Primary Medicine and Pharmacy
Year:
2014
Type:
Article
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