Artifactual Hyperbilirubinemia due to Paraprotein Interference in a Case of Multiple Myeloma / 임상검사와정도관리
Journal of Laboratory Medicine and Quality Assurance
; : 133-137, 2013.
Article
in Ko
| WPRIM
| ID: wpr-48475
Responsible library:
WPRO
ABSTRACT
When analyzing samples containing paraproteins, various interference effects are encountered in the clinical laboratory. Precipitation of paraproteins mostly interferes with the assays that use photometric detection. Herein, we present a case of a patient with multiple myeloma who had paraproteins and spuriously elevated total bilirubin levels (31.1 mg/dL), which were measured by using Roche total bilirubin assay on the Modular DPE (Roche Diagnostics, Switzerland) chemical analyzer. The total bilirubin concentration reduced from 31.1 mg/dL to 1.5 mg/dL, when tested after three fold dilution of the sample on Modular DPE chemical analyzer.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Paraproteinemias
/
Bilirubin
/
Paraproteins
/
Hyperbilirubinemia
/
Multiple Myeloma
Limits:
Humans
Language:
Ko
Journal:
Journal of Laboratory Medicine and Quality Assurance
Year:
2013
Type:
Article