Observation on analgesic effect of oxycodone acetaminophen and celecoxib for military training injury / 局解手术学杂志

ABSTRACT

Objective To investigate the analgesic effect and safety of oxycodong acetaminophen and celecoxib on the military training injury,and provide a reliable evidence for the usage of drugs. Methods 90 patients were randomly divided into 3 groups(n=30),which were celecoxib group,oxycodone acetaminophen group and placebos group. The efficacy and safety were evaluatedv by the visual analogue score (VAS) before using the drug and the 2nd day,4th day,6th day,8th day after giving drugs. Results The VAS of celecoxib group at each time point were less than that of oxycodong acetaminophen group. And there were nearly no adverse reactions of celecoxib group. The differences were statistically significant (P<0. 05). Conclusion The celecoxib has a good analgesic effect on military training injury and less adverse reactions. Which should be the first choice for paitents suffering from the pain of military training injury.