Randomized Control Trial of Xuebijing Injection in Adjuvant Treatment of Children with Perforated Appen-dicitis / 中国药房
China Pharmacy
; (12): 3278-3279, 2015.
Article
in Zh
| WPRIM
| ID: wpr-500988
Responsible library:
WPRO
ABSTRACT
OBJECTIVE:
To evaluate the efficacy and safety of Xuebijing injection in the adjuvant treatment of children with perforated appendicitis.METHODS:
72 children with perforated appendicitis in the Dept. of Pediatric General Surgery of our hospi-tal were enrolled into a prospective clinical trial,and randomly divided into experimental group (n=36) and control group (n=36). Both groups received the emergency surgery and anti-infective treatment;experimental group had additionally given Xuebijing injection. The white blood cell count (WBC),C-creation protein (CRP) and procalcitonin (PCT),liver and kidney function and hospitalization time before and after treatment were collected and adverse reaction.RESULTS:
The WBC in experimental group af-ter 3 and 6 d of treatment was respectively(13.6±3.4)×109 L-1 and(9.1±4.2)×109 L-1,CRP was respectively(52.7±13.6)mg/L and(8.5±3.3)mg/L,the PCT(0.3±0.2)ng/ml,and the hospitalization time after 3 d were lower than control group,with signifi-cant difference(P0.05). There was 1 case with itch of skin but with no severe ADR.CONCLUSIONS:
Xuebijing injection in the adjuvant treatment of children with perforated ap-pendicitis is safe and effective.
Full text:
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Index:
WPRIM
Type of study:
Clinical_trials
Language:
Zh
Journal:
China Pharmacy
Year:
2015
Type:
Article