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Preoperative Thyroid-stimulating Hormone Levels as a Predictor of Thyroid Carcinoma / 대한내분비외과학회지
Korean Journal of Endocrine Surgery ; : 220-223, 2010.
Article in Korean | WPRIM | ID: wpr-51771
ABSTRACT

PURPOSE:

This study investigated the effects of serum thyroid-stimulating hormone (TSH) levels in predicting malignancy-associated differentiated thyroid cancer (DTC) and benign thyroid nodules.

METHODS:

Between January 2005 and December 2007, 346 patients underwent thyroid surgery at one hospital. Their records were retrospectively reviewed.

RESULTS:

Sixty-nine percent (237 of 346) of the patients had DTC. The mean preoperative TSH level was higher than in the malignant group (5 uIU/ml vs 0.4 uIU/ml). The rate of malignancy was the 71% in patients with TSH levels >5 uIU/ml. The TSH level of DTC with metastasis of the lymph node was higher than that with non-metastasis (3.08 uIU/ml vs 2.09 uIU/ml, P<0.01)

CONCLUSION:

The likelihood of DTC increases with higher serum TSH concentration. Serum TSH level might be useful in predicting malignant nodular thyroid lesion.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Thyroid Gland / Thyroid Neoplasms / Thyrotropin / Retrospective Studies / Thyroid Nodule / Lymph Nodes / Neoplasm Metastasis Type of study: Observational study / Prognostic study / Risk factors Limits: Humans Language: Korean Journal: Korean Journal of Endocrine Surgery Year: 2010 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Thyroid Gland / Thyroid Neoplasms / Thyrotropin / Retrospective Studies / Thyroid Nodule / Lymph Nodes / Neoplasm Metastasis Type of study: Observational study / Prognostic study / Risk factors Limits: Humans Language: Korean Journal: Korean Journal of Endocrine Surgery Year: 2010 Type: Article