Preoperative Thyroid-stimulating Hormone Levels as a Predictor of Thyroid Carcinoma / 대한내분비외과학회지
Korean Journal of Endocrine Surgery
;
: 220-223, 2010.
Article
in Korean
| WPRIM
| ID: wpr-51771
ABSTRACT
PURPOSE:
This study investigated the effects of serum thyroid-stimulating hormone (TSH) levels in predicting malignancy-associated differentiated thyroid cancer (DTC) and benign thyroid nodules.METHODS:
Between January 2005 and December 2007, 346 patients underwent thyroid surgery at one hospital. Their records were retrospectively reviewed.RESULTS:
Sixty-nine percent (237 of 346) of the patients had DTC. The mean preoperative TSH level was higher than in the malignant group (5 uIU/ml vs 0.4 uIU/ml). The rate of malignancy was the 71% in patients with TSH levels >5 uIU/ml. The TSH level of DTC with metastasis of the lymph node was higher than that with non-metastasis (3.08 uIU/ml vs 2.09 uIU/ml, P<0.01)CONCLUSION:
The likelihood of DTC increases with higher serum TSH concentration. Serum TSH level might be useful in predicting malignant nodular thyroid lesion.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Thyroid Gland
/
Thyroid Neoplasms
/
Thyrotropin
/
Retrospective Studies
/
Thyroid Nodule
/
Lymph Nodes
/
Neoplasm Metastasis
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Endocrine Surgery
Year:
2010
Type:
Article
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