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Acute pulmonary injury caused by echinococcus granulosus cyst fluid / 中国病理生理杂志
Article in Chinese | WPRIM | ID: wpr-520653
Responsible library: WPRO
ABSTRACT

AIM:

to establish an animals model of pulmonary embolism caused by echinococcus granulosus (E.g)cyst fluid.

METHODS:

Cyst fluid were isolated from sheep liver . Twenty-one rabbits were randomized into 3 groups group Ⅰ(saline group), group Ⅱ(clear cyst fluid group), group Ⅲ (sand-contained cyst fluid group). Operation was performed on each animal to place a femoral artery catheter and a femoral vein catheter. Saline, clear cyst fluid or sand-contained cyst fluid were given to rabbits at a dose of 3 mL/kg body weigh . Observations were then made at 10, 30, 60 minutes to determine the changes of MAP, blood gas and vaso-active substance. Then ECT scanning image was obtained .After observation, all animals were killed and the lungs were harvested for histological examination by light microscopy.

RESULTS:

Remarkable decline of PaO 2 , MAP and rise of TXB 2, 6-keto-PGF 1? were observed in group Ⅲ and group Ⅱ(P

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Pathophysiology Year: 1986 Type: Article
Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Pathophysiology Year: 1986 Type: Article