Acute pulmonary injury caused by echinococcus granulosus cyst fluid / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)1986.
Article
in Chinese
| WPRIM
| ID: wpr-520653
ABSTRACT
AIM:
to establish an animals model of pulmonary embolism caused by echinococcus granulosus (E.g)cyst fluid.METHODS:
Cyst fluid were isolated from sheep liver . Twenty-one rabbits were randomized into 3 groups group Ⅰ(saline group), group Ⅱ(clear cyst fluid group), group Ⅲ (sand-contained cyst fluid group). Operation was performed on each animal to place a femoral artery catheter and a femoral vein catheter. Saline, clear cyst fluid or sand-contained cyst fluid were given to rabbits at a dose of 3 mL/kg body weigh . Observations were then made at 10, 30, 60 minutes to determine the changes of MAP, blood gas and vaso-active substance. Then ECT scanning image was obtained .After observation, all animals were killed and the lungs were harvested for histological examination by light microscopy.RESULTS:
Remarkable decline of PaO 2 , MAP and rise of TXB 2, 6-keto-PGF 1? were observed in group Ⅲ and group Ⅱ(P
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Controlled clinical trial
Language:
Chinese
Journal:
Chinese Journal of Pathophysiology
Year:
1986
Type:
Article
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