Effect of Qingxin capsule on differentiation of Th cell in the course of viral myocarditis / 中国免疫学杂志
Chinese Journal of Immunology
; (12)1985.
Article
in Zh
| WPRIM
| ID: wpr-541329
Responsible library:
WPRO
ABSTRACT
Objective:To investigate the changes of Th cell differentiation in the VMC and interference effect of Qingxin capsule on them.Methods:BALB/c mouses with different courses of VMC were established, after treated with Qingxin capsule, the cardiac pathological changes were observed by light microscope and transmisson electron microscope,levels of IL-2,IL-4,IL-10 and IFN-? in blood serum were detected by ELISA.Results: Whatever in acute stage or recovery stage of VMC, the myocard pathological changes of mouses were lighter after treated with Qingxin capsule;moreover, levels of IFN-? and IL-2 in blood serum of mouses with VMC decreased significantly(P0.05).Conclusion:Qingxin capsule can restore the balance of Th1 and Th2 cells through inhibiting reaction of Th1 and enhancing reaction of Th2.
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Index:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Immunology
Year:
1985
Type:
Article