Lymphomas with CARMA1, BCL10, MALT1 and NF-?B signaling pathway / 中国癌症杂志
China Oncology
; (12)2006.
Article
in Zh
| WPRIM
| ID: wpr-545393
Responsible library:
WPRO
ABSTRACT
CARMA1, BCL10 and MALT1 are lymphocyte-specific signaling molecules of NF-?B pathway.The abnormalities of those molecules such as gene mutation, rearrangement, translocation or amplification often connect with the lymphoma genesis. This article reviewed the physiological function of those molecules and the relationship between genetic abnormalities and lymphoma genesis, also with present target-treatment research and new gene medicine development.
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Index:
WPRIM
Language:
Zh
Journal:
China Oncology
Year:
2006
Type:
Article