Therapeutic effects of traditional Chinese medicine on nontraumatic necrosis of femoral head in different stages / 解放军医学杂志

ABSTRACT

Objective To investigate the clinical therapeutic effects of traditional Chinese medicine on different stages of nontraumatic necrosis of femoral head.Methods The clinical data were retrospectively analyzed of 359 patients(239 males and 120 females,aged 16-69 years,averaged 40.6) suffering from nontraumatic necrosis of femoral head,admitted to our hospital from Aug.2001 to Aug.2008,and treated with traditional Chinese medicine.The patients were divided into five stages(0,1,2,3,and 4) according to Huang Changlin's and Ficat's clinical diagnostic criteria.The age,gender and disease course of patients in different stages were of comparability.All the patients were treated with traditional Chinese medicine for 3-6 months and followed up for 1-2 years,and the final therapeutic effects were evaluated by the comprehensive evaluation criteria.Results The clinical cure rates in patients of stages 0,1,2,3 and 4 were 44.9%,36.1%,30.5%,0% and 0%,and the effective rates were 97.8%,80.6%,75.6%,63.6% and 50.0%,respectively.The total cure rate was 25.3%,and the total effective rate was 76.3%.The therapeutic effect in patients of stage 0 was better than those of stages 1 and 2(P0.05).Conclusions The therapeutic effect of traditional Chinese medicine is remarkable on the patients with nontraumatic necrosis of femoral head in stages 0,1 and 2,but not in stages 3 or 4.Traditional Chinese medicine may increase the cure rate of early stage patients,and improve the symptoms of advanced stage patients.