Optimization of the Extraction Technology of Total Lignans from Pine Needles of Cedrus deodara by Re-sponse Surface Methodology / 中国药房
China Pharmacy
;
(12): 939-941,942, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-605654
ABSTRACT
OBJECTIVE:
To optimize the extraction technology of total lignans from pine needles of Cedrus deodara. METH-ODSUsing ethanol volume fraction,ratio of liquid to solid and extraction time as response factor,the content of total lignans as response value,the response surface methodology test was conducted based on Box-Behnken design to optimize the extraction tech-nology of total lignans from pine needles of C. deodara.RESULTS:
The optimal extraction technology was as follows as ethanol volume fraction of 78%,ratio of liquid to solid 25∶1,extraction time 1.75 h. The content of total lignans from pine needles of C. deodara was 99.2 mg/g,which was close to predicted value 100.49 mg/g,with relative deviation of 0.65%.CONCLUSIONS:
Op-timized extraction technology of pine needles of C. deodara by response surface methodology is feasible and stable,and has good predictability.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
China Pharmacy
Year:
2016
Type:
Article
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