Classification of polypoidal choroidal vasculopathy and its influencing factors / 中华眼底病杂志
Chinese Journal of Ocular Fundus Diseases
;
(6): 230-234, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-609630
ABSTRACT
Polypoidal choroidal vasculopathy (PCV) is a fundus disease characterized by choroidal anomalous branch vascular network and terminal polypoidal dilatation.According to its fundus feature,lesion location,imaging feature and disease progression,PCV can be divided into different types or stages.It can be divided into hemorrhage and exudation PCV according to the fundus features,into macular,peripapillary,periphery and mixed types according to the lesion locations.It can also be divided into type 1 and 2 according to the ICGA (indocyanine green angiography) manifestations,and can be classified as early stage and late stage according to disease progression.There were different correlations between different types of PCV and some risk genetic loci,such as ARMS2 (age-related macular degeneration factor 2)/HTRA1 (high temperature essential protein A1),C2,complement factor B,complement factor H,and elastin genes.The response to therapy and prognosis are also different between different types.It is important to further study the clinical classification of PCV,to explore the genetic characteristics,influencing factors and treatment or prognosis features of different types of PCV.The results will improve the differential diagnosis of PCV,and the effectiveness of individualized treatment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Chinese Journal of Ocular Fundus Diseases
Year:
2017
Type:
Article
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