Value of aortic dissection detection risk score combined with D-dimer in patients with suspected acute aor-tic dissection / 实用医学杂志
The Journal of Practical Medicine
; (24): 2213-2216, 2017.
Article
in Zh
| WPRIM
| ID: wpr-617105
Responsible library:
WPRO
ABSTRACT
Objective To assess the diagnostic value of combining aortic dissection detection risk score (ADDRS)with D-dimer in patients with suspected acute aortic dissection(AAD). Methods We retrospectively identified 525 patients with chest pain and with calculated ADDRS and available D-dimer on admission between January 2015 and December 2016. ADDRS ≤1 was defined as ′low probability′ and that >1 as ′high probability′. Results AAD were diagnosed in 106(20.2%)patients. In patients with ADDRS of 0,1 case of AAD was identi-fied and in those with ADDRS of 1,40 were identified while in 76 patients with ADDRS of 2 and 3,71 cases of AAD were identified. D-dimer with threshold of 0.5 mg/L had a negative predictive value of 100%and a specificity of 76.6% in patients with ADDRS of 0. In patients with ADDRS of 1,D-dimer had a negative predictive value of 98.6%. D-dimer showed a negative predictive value of 99.6% and a positive predictive value of 22.3% in patients with low probability. Conclusions High ADDRS benefits confirming AAD. Low ADDRS combined with negative D-dimer is safe and efficient for ruling out AAD ,while low ADDRS with positive D-dimer needs further aortic imaging.
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Index:
WPRIM
Type of study:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
Language:
Zh
Journal:
The Journal of Practical Medicine
Year:
2017
Type:
Article