A Successful Case of a High Anti A/B Antibody Titer ABO Incompatible Kidney Transplantation Patient Who Received a Kidney from a Hepatitis B Carrier / 대한이식학회지
The Journal of the Korean Society for Transplantation
;
: 184-189, 2016.
Article
in Korean
| WPRIM
| ID: wpr-65262
ABSTRACT
Kidney transplantation (KTP) lowers the mortality and morbidity of patients with end-stage renal disease. Post-transplantation infection and antibody mediated rejection (AMR) are the most common complications. Hepatitis B surface antigen (HBsAg) positive carrier donors and high anti A/B antibody titer ABO incompatible KTP could lead to recipient hepatitis B virus (HBV) infection and AMR. Here, we report a case of successful KTP in a 41-year-old male with a high titer of ABO incompatible and HBsAg positive donor. He underwent seven rounds of plasmapheresis, low dose intravenous immunoglobulin and rituximab treatment to inhibit antibody production and remove antibodies from the serum, after which he was administered anti-viral agent for HBV prophylaxis. The recipient maintained successful allograft function for 6 months after transplantation; therefore, we report that desensitization and anti-viral treatment achieved successful outcome in a 1512 anti A/B antibody titer ABO incompatible and hepatitis B carrier donor KTP.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Tissue Donors
/
Immunoglobulins
/
Hepatitis B virus
/
Mortality
/
Kidney Transplantation
/
Plasmapheresis
/
Allografts
/
Rituximab
/
Hepatitis
/
Hepatitis B
Type of study:
Prognostic study
Limits:
Adult
/
Humans
/
Male
Language:
Korean
Journal:
The Journal of the Korean Society for Transplantation
Year:
2016
Type:
Article
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