Recent advances in biomarkers of postmenopausal osteoporosis / 中华检验医学杂志

ABSTRACT

Postmenopausal osteoporosis(PMOP)is a primary metabolic disorder of bone in postmenopausal women which is characterized by osteopenia, destruction of bone microstructure, increased bone fragility and fracture.PMOP is the major cause of joint pain and disability in middle-aged and elderly women.The research shows that early biomarkers can provide clinical evidence for early diagnosis of PMOP, assess fracture risk and evaluate treatment effect.In this paper, the latest advances in the application of PMOP biomarkers are described from the aspects of PMOP hormone correlation index and bone metabolism.