Study on Diterpenoid Alkaloids from the Roots of Aconitum Straminiflorum / 中国药师
China Pharmacist
;
(12): 538-540, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-669807
ABSTRACT
Objective:
To study the chemical constituents of Aconitum straminiflorum.Methods:
The air-dried roots of A. stra-miniflorum were powdered and extracted three times with 90% ethonal under reflux. After the removal of the solvent under reduced pressure,the crude extract was dissolved in 1. 5% HCl solution(7 L). The acidic solution was basified to pH 9. 0 with ammonia (25%)and extracted with CHCl3 to obtain crude extract of total alkaloids after the removal of CHCl3 . The compounds were isolated and purified by column chromatography and identified based on spectral analysis( MS,1 H-üMR and 13 C-üMR).Results:
Totally 7 compounds were isolated from A. straminiflorum,and characterized as aconosine(1),13-deoxyludaconitine(2),dolaconine(3), ezochasmanine(4),talatisamine(5),scopaline(6)and cammaconine(7),respectively.Conclusion:
Seven diterpenoid alkaloids are isolated from A. Straminiflorum for the first time.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacist
Year:
2015
Type:
Article
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