Association between rheumatoid arthritis and shared epitope of HLA-DRB1 gene in Shandong population / 中华风湿病学杂志
Chinese Journal of Rheumatology
;
(12)2003.
Article
in Chinese
| WPRIM
| ID: wpr-682174
ABSTRACT
Objective To investigate the association between rheumatoid arthritis (RA) and the presence of the shared epitope (SE) of HLA DRB1 gene in Han nationality of Shandong population.Methods The method of DNA amplification with sequence specific primers (PCR SSP) was used to determine 17 alleles of HLA DRB101,04,10 genotypes in 132 RA patients and 130 healthy controls from the Han nationality population in Shandong.Results The frequencies of SE were significantly increased in RA patients compared with controls (50 0% vs 22 3%, P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Rheumatology
Year:
2003
Type:
Article
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