Gastrointestinal microflora and leukemia / 国际儿科学杂志

ABSTRACT

Gastrointestinal microflora are the largest and the most complicated micro-ecosystem in hu-man′s body. It is parasitic on the human′s gastrointestinal tract,and help the host to finish many physiological and biochemical functions. The patients who are diagnosed with leukemia will have large change in their gastro-intestinal microflora. After allogeneic hematopoietic stem cell transplantation,patients can suffer from acute graft versus host disease,and studies have shown that gastrointestinal microflora play an important role in reducing the incidence of acute graft-versus-host disease. Maintaining the balance of gastrointestinal microflora and using it as the target for leukemia treatment can prolong the survival period of leukemia patients. This phenomenon mani-fests that the gastrointestinal microflora is closely associated with leukemia. It will provide new strategy to leuke-mia′s treatment by studying the correlation between gastrointestinal microflora and leukemia.