Early diagnostic value of carotid IMT and hemodynamic indexes for ischemic cerebrovascular diseases / 心血管康复医学杂志

ABSTRACT

Objective:To explore early diagnostic value of carotid intima-media thickness (IMT) and hemodynamic indexes for ischemic cerebrovascular diseases .Methods:A total of 42 cases with cerebral infarction (CI group) ,98 cases with transient ischemic attack (TIA group) and 40 cases without cerebrovascular disease were enrolled as nor-mal control group ,and all patients were received and cured in our hospital from Jan 2014 to Jan 2017. All subjects received Doppler ultrasonography after hospitalization ,IMT at common carotid artery (CCA) bifurcation and its distal end ,peak systolic velocity (PSV) ,end-diastolic velocity (EDV) ,vascular pulsatility index (PI) ,vascular re-sistance index (RI) and ratio of peak wave ascending branch slope to descending branch slope (S1/S2) at CCA ,in-ternal carotid artery (ICA) and vertebral artery (VA) were measured and compared among three groups ,and diag-nostic value of IMT for CI and of hemodynamic indexes for TIA were analyzed .Results: Compared with normal control group and TIA group ,there were significant rise in IMT of CCA bifurcation [ (0.87 ± 0.05) mm ,(0.87 ± 0.04) mm vs.(1.04 ± 0.05) mm] and IMT of CCA bifurcation distal end [ (0.77 ± 0.06) mm ,(0.78 ± 0.04) mm vs.(0.90 ± 0.02) mm] in CI group , P＝ 0.001 all.There were no significant difference in PSV ,PI and RI at CCA ,ICA and VA among three groups , P＞0. 05 all.EDV and S1/S2 at CCA ,ICA and VA of three groups were all accorded with TIA group＜ CI group＜ normal control group ,and there was significant difference between any two groups , P＜0. 01 all .Sensitivity ,specificity ,negative and positive predictive value of IMT of CCA bifurcation diagnosing CI were higher than those of IMT of CCA bifurcation distal end ,but there were no significant differ-ence , P＞0. 05 all.Conclusion:During Doppler ultrasonography ,detecting carotid IMT , EDV and S1/S2 at CCV , ICA and VA contribute to diagnosing cerebral infarction and TIA .