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Association between morning surge of systolic blood pressure and white matter lesions in elderly hypertensive patients / 中华老年心脑血管病杂志
Chinese Journal of Geriatric Heart Brain and Vessel Diseases ; (12): 268-270, 2018.
Article in Chinese | WPRIM | ID: wpr-709109
ABSTRACT
Objective To study the association between morning surge (MS) of systolic blood pressure (SBP) and white matter lesions in elderly essential hypertensive (EH) patients.Methods Three hundred and thirty-seven elderly EH patients from Zhangqiu of Shandong Province were divided into MS group (n=150) and non-MS group (n=187).Their 24 h ambulatory SBP was monitored.Their white matter hyperintensity (WMH) was assessed according to their brain MRI.Results The total WMH,periventricular WMH,and deep WMH were significantly higher in MS group than in non-MS group (P<0.01).The MS of SBP was positively related with the total WMH,periventricular WMH,and deep WMH (r=0.561,r=0.563,r=0.283,P<0.01),and was an independent risk factor for total WMH,periventricular WMH,and deep WMH after adjustment for confunders (r=0.479,r=0.486,r=0.208,P<0.01).Conclusion MS of SBP is an independently risk factor for WMH in elderly EH patients.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Risk factors Language: Chinese Journal: Chinese Journal of Geriatric Heart Brain and Vessel Diseases Year: 2018 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Risk factors Language: Chinese Journal: Chinese Journal of Geriatric Heart Brain and Vessel Diseases Year: 2018 Type: Article