Effect of combined use of Chinese and western medicine on follicular development and ovulation in infertility patients / 中国基层医药

ABSTRACT

Objective To investigate the effect of combined use of Chinese and western medicine on follicular development and ovulation in infertility patients.Methods The clinical data of 86 infertile patients treated in special clinic of the No.155 Central Hospital of PLA from January 2014 to June 2017 were retrospectively analyzed.According to the treatment method,the patients were divided into control group (n =40) and observation group (n =46).The control group was given corresponding westem medicine treatment,the observation group was treated with Chinese medicine on the basis of the control group,and all patients received ultrasound examination before and after treatment.At the end of treatment,the dominant follicle,ovulation rate,pregnancy rate,luteinized unrupture follicle syndrome and ovarian hyperstimulation syndrome were recorded and compared between the two groups by ultrasonography.The adverse reactions of the two groups were recorded during the treatment.Results (1) Ultrasound monitoring showed that the dominant follicle rate(95.65％),ovulation rate(78.26％) and pregnancy rate(56.52％) in the observation group were significantly higher than those in the control group (55.00％,50.00％ and 30.00％) (x2 =19.811,P ＜ 0.001;x2 =7.523,P ＜ 0.001;x2 =6.102,P ＜ 0.001);(2) The incidence rate of adverse reactions in the observation group was 6.52％,which was significantly lower than 45.00％ in the control group,the difference was statistically significant(x2 =17.164,P ＜ 0.001).Conclusion The combined treatment of Chinese and western medicine on infertility patients has more significant clinical efficacy.Under the guidance of ultrasound monitoring,the drug dosage and time can be more accurate,which can further improve the pregnancy rate with a certain security,it is worth widely used in clinical.